Anatomy and Cell BiologyMentor Name: Uma Sankar
- Internship Location:
- Pre Professional Interests Preferred:
Pre-Dentistry, Pre-Medicine, Pre-Pharmacy, Pre-Physical Therapy, Pre-Veterinary Medicine
- Dress Code:
- Casual with legs and feet covered for protection
- Majors Preferred:
Biology, Biomedical Engineering, Biotechnology
- Hours per week:
- Flexible within regular work hours
- Calcium/calmodulin-dependent protein kinase (CaMK) signaling in bone remodeling, osteoarthritis, and prostate cancer. We study the role of a protein kinase, CaMKK2, in bone cell biology. Loss or inhibition of CaMKK2 stimulates bone accumulation and suppresses inflammation in mice. Projects being pursued in the lab include understanding how CaMKK2 inhibition using a drug promotes healing of fractures, protects from osteoarthritis, prevents osteoporosis, and halts bone metastasis of prostate cancer.
- Internship Duties:
- Preparing solutions, molecular biology techniques, qRT-PCR, cell culture, SDS-PAGE, western blotting, microscopy, micro-CT imaging, histology, bone histomorphometry, mouse genotyping, harvest of tissue and cells from mice, etc. The intern will perform supervised experiments initially and transition to independent experiments when fully trained.
- Good basic background in biology and chemistry. Some wet lab experience is desirable, but not necessary.