Physical TherapySupervisor: Robyn Fuchs
- Internship Location:
Health and Human Sciences
- Pre Professional Interests Preferred:
Pre-Medicine, Pre-Nursing, Pre-Physical Therapy
- Dress Code:
- Lab-safe clothing
- Majors Preferred:
Biology, Biomedical Engineering, Chemistry, Medical Humanities and Health Studies, Neuroscience, Nursing
- Hours per week:
- Flexible based on student needs
- Specific days/times required. Lab meetings will be scheduled based on student availability,
- Our lab focuses on how exercise and pharmaceutical agents impact the growing skeleton. We use different genetically modified animal models to help answer our research questions. At this time we are studying the serotonin transporter (5-HTT) which works to move serotonin molecules into cells and is found on cells in the brain, intestines and skeleton. The transporter is a common target of drugs for the treatment of conditions such as anxiety and depression, with popular anti-depressant drugs including Prozac and Zoloft. These drugs are effective in managing depression and anxiety; however, we have previously found blocking of the serotonin transporter by these drugs may cause bones to be smaller and weaker which is a concern in terms of an individual's risk for bone fracture and osteoporosis. You will be involved in studies that use genetically modified mouse models to disrupt the serotonin transporter in select tissues and cells in order to localize the origin of the bone side-effects of drugs targeting the serotonin transporter.
- Internship Duties:
- Student will learn how to design a study, analyze data, perform a variety of different imaging techniques to evaluate bone tissue, and learn how to do histomorphometry of bone tissue. All techniques used in the lab will be taught, no prior experience is required
- Have the ability to learn powerpoint, word, and excel if they don't already know how to use. All other software will be taught as needed to complete research in the lab.