Orthopedic SurgeryMentor Name: Melissa Kacena
- Internship Location:
- Pre Professional Interests Preferred:
Pre-Dentistry, Pre-Medicine, Pre-Nursing, Pre-Occupational Therapy, Pre-Physical Therapy, Pre-Veterinary Medicine
- Dress Code:
- Hours per week:
- Flexible within regular work hours
- My laboratory's overall research goal is to improve the understanding of the interaction of the bone and hematopoietic systems, thereby potentially improving the treatment of metabolic bone disease, hematopoietic disorders, and fracture healing. To achieve this goal, our research focuses in five areas: 1) The role of megakaryocytes, megakaryocyte growth factors and their receptors in bone homeostasis; 2) Osteoblasts and the hematopoietic stem cell niche; 3) Lytic disease in cancer of the bone (breast cancer, osteosarcoma, and multiple myeloma); 4) Translational/clinical studies examining the genetic regulation of skeletal homeostasis; and 5) The molecular mechanisms underlying bone repair/fracture healing.
- Internship Duties:
- Students would learn many of the fundamental wet laboratory procedures: Sterile technique, cell culture, PCR, histology etc. Some projects involve working with animals and may have a surgical component. Some projects students would interact with clinicians as well as PhD faculty members. Chart reviews are also routinely conducted. In our laboratory we examine how bone cells interact with blood cells. We utilize many in vitro and in vivo models.We are also interested in rheumatoid arthritis, bone healing, and bone cancer (primarily osteosarcoma, breast cancer, and mulitple myeoloma).
- Must be willing to work with mice. Should have larger blocks of time available during the 8a-6p time frame (at least 3 hour blocks)