EndocrinologySupervisor: Imranul Alam
- Internship Location:
- Pre Professional Interests Preferred:
- Dress Code:
- Casual dress (long pants and closed-toe shoes) and personal protective equipment (lab coat, gloves and safety glasses)
- Majors Preferred:
Anthropology, Biology, Biomedical Engineering, Biotechnology, Chemistry, Exercise Science, Forensic and Investigative Sciences, Health Sciences, Neuroscience, Public Health
- Hours per week:
- Flexible based on student needs
- Flexible within regular work hours
- Discover innovative treatment strategies for bone and mineral diseases through basic and pre-clinical research. Our laboratory focuses on basic and pre-clinical research related to both common and rare bone and mineral diseases. We employ various cutting-edge cell and molecular biology methodologies; we also utilize genetics, biochemical assays, and state-of-the-art imaging techniques. In addition, we create mouse models of human bone disorders by genetic engineering and test various drugs in these mouse models for potential therapeutic targets in humans. Our main goal is to understand better the developmental process and molecular mechanisms as well as to discover novel treatment strategies for common (osteoporosis) and rare (osteopetrosis) bone diseases.
- Internship Duties:
- Intern will participate in multiple projects currently ongoing in the laboratory, learn numerous techniques in an interactive way, and perform supervised as well as independent experiments. Some of the typical duties for intern involve DNA and RNA isolation, standard and real-time PCR, gene expression analysis, electrophoresis, and DNA sequencing and genotyping. Intern will also learn basic cell culture techniques as well as targeted gene over-expression and silencing in bone cells and perform biochemical and histological measurements, in-vivo and ex-vivo skeletal imaging, analysis of bone phenotypes, animal breeding, tissue dissection, and surgery. Data analysis and presentation during lab meeting are routinely involved.
- Some basic laboratory experience is helpful, but not required. Extensive training will be provided, but eager to learn, good communication skills, and willingness to work both independently and with other lab members are essential.