Medicine (Hematology/Oncology) and Cellular and Integrative PhysiologySupervisor: Heather O'Leary
- Internship Location:
- Dress Code:
- Closed-toe shoes
- Majors Preferred:
Biology, Biotechnology, Health Sciences
- Hours per week:
- Flexible within regular work hours
- We study normal and cancer blood cells and how understanding their native environment can help us pick better therapeutic targets. Normal and malignant (cancerous) blood cells reside in environments where the native oxygen (O2) levels are significantly lower than the room air we breathe (~3% O2 compared to ~21% O2, respectively). We determined that the cells phenotype (how they look) and function (how they behave) are different in their native low levels vs room air. Therefore, we developed novel technology to study normal and malignant cells in their native low 02. We use this technology to 1) Determine how oxygen tension alters how the cells grow/divide/behave/function 2) identify how cells grow/divide/behave/function in native low O2 and 3) use the knowledge that we gain to facilitate using low oxygen harvested cells for cellular therapy.
- Internship Duties:
- Cell culture, experiments, collaborating with post-doc and technician, flow cytometry, data analysis, and potential assistance with animal experiments.
- Enthusiasm for learning and science.